Thiamin for Nervous Disorders

Thiamin (also spelled "thiamine") is a water-soluble B-complex vitamin, previously known as vitamin B1 or aneurine. Thiamin may most commonly be known for treating Beriberi.

But Thiamin is involved in other body functions, including: nervous system and muscle functioning; flow of electrolytes in and out of nerve and muscle cells (through ion channels); multiple enzyme processes (via the coenzyme thiamin pyrophosphate); carbohydrate metabolism; and production of hydrochloric acid (which is necessary for proper digestion). Because there is very little thiamin stored in the body, depletion can occur as quickly as within 14 days.

So how does Thiamine play an important role in nervous disorders? Researchers feel it is because of its role in the synthesis of acetylcholine (via the production of acetyl CoA), an important neurotransmitter. With a lack of vitamin B1, the nerves are more sensitive to inflammation. It is said therefore, that increased Thiamine intake may be suggested for numerous mental illnesses and problems that affect the nerves. These include alcoholism and its nerve problems, multiple sclerosis, Bell's palsy (a facial nerve paralysis), and neuritis. Treatment with thiamine, for example, has been helpful in decreasing the sensory neuropathy that accompanies diabetes and in lessening the pain of trigeminal neuralgia. Thiamine also has a mild diuretic effect and is supportive of heart function, so it is suggested in the treatment program for many cardiovascular problems.

Since Thiamine is eliminated through the skin somewhat, doses of over 50-100 mg. per day may help repel insects such as flies and mosquitos from those with "sweet blood." Other uses for increased Thiamine include treatment of stress and muscle tensions, diarrhea, fever and infections, cramps, and headaches

Thiamine is used commonly to improve healing after dental (or, often, any) surgery.

Dietary sources of Thiamin include beef, brewer's yeast, legumes (beans, lentils), milk, nuts, oats, oranges, pork, rice, seeds, wheat, whole grain cereals, and yeast. In industrialized countries, foods made with white rice or white flour are often fortified with thiamin (because most of the naturally occurring Thiamin is lost during the refinement process).

Conditions resulting in an increased requirement for Thiamin include strenuous physical exertion, fever, pregnancy, breast-feeding, and adolescent growth. Such conditions place individuals with marginal Thiamin intake at risk for developing symptomatic Thiamin deficiency.

Recently, malaria patients in Thailand were found to be severely thiamin deficient more frequently than non-infected individuals. Malarial infection leads to a large increase in the metabolic demand for glucose. Because Thiamin is required for enzymes involved in glucose metabolism, the stresses induced by malarial infection could exacerbate Thiamin deficiency in predisposed individuals. HIV-infected individuals, whether or not they had developed AIDS, were also found to be at increased risk for Thiamin deficiency. The lack of association between Thiamin intake and evidence of deficiency in these HIV-infected individuals suggests that they had an increased requirement for Thiamin.

Is Thiamin merely a supplement that helps with rare diseases? It seems not as scientists are discovering more and more how it benefits the body.

About the Author: R. Fredriksen is the Vice President of Nutrition Dome, a leading provider of Jarrow Formulas, Met-Rx, Pioneer Nutritional Formulas, Lipodrene and other quality supplements. For more information, please visit www.nutritiondome.com.

Natural Medicine and Depression

Millions of individuals suffer from clinical or symptomatic depression. If you are one of them, you can experience great benefit from some specific attention to their own health as well as guidance from a health professional who understands the basic tenets of natural medicine.

Natural medicine is consistent with the rhythms of nature and how nature is organized. Historically, there has been a commitment in medicine to do no harm, and when you are using natural substances such as herbs and working at a gradual pace, the likelihood of doing harm is almost completely eliminated.

Because depressions symptoms can be all over the board and sometimes quite contrary to each other, finding the right herbal medicine for treatment can be tricky. For instance, some symptoms for one may include chronic fatigue syndrome, insomnia, excessive sleep, loss of appetite, excessive appetite, headaches, backaches, joint aches, bowel disorders, as well as feelings of worthlessness and inadequacy. The next person will complain of tension, stress, chronic headaches, chronic stomach aches, bowel problems, chronic nutritional deficiencies, chronic allergies, chronic physical disorder, poor diet, excessive sugar and caffeine intake, endocrine disorder such as hypothyroidism, endometriosis, lack of sun exposure, and assaults from the environment such as toxic metals.

Naturopaths will often start with the individual’s weakest physical link before prescribing dietary changes, exercise, nutritional supplements, homeopathy and/or specific herbs or herbal combinations for treating depression or its associated symptoms.

Some of the observations these physicians are discovering as the common cause of depression are the following:

1. Hypothyroidism - Patients suffering from hypothyroidism very often feel like they cannot cope, life is simply too much, and find themselves withdrawing from the world. Typically, patients experience a tremendous mental shift after appropriate treatment for hypothyroidism.

There are certain nutrients, which are used to enhance thyroid activity. Kelp, seaweed, which contains iodine, is often useful in supplementing thyroid function. L-tyrosine, an amino acid, is also effective in stimulating proper thyroid function and fighting depression associated with depressed thyroid function. A naturally oriented health care practitioner may also prescribe a thyroid glandular. The B vitamins are also very important to improve energy and assure proper glandular function.

Adaptogenic herbs, specifically Eleutherococcus senticosus, better known as Siberian ginseng may also be considered in cases of hypothyroidism. This herb helps to regulate the entire endocrine system, including the thyroid and adrenal function.

2. Potassium deficiency, in particular, is another common cause of depression. Women who are particularly low in potassium can have acute episodes of depression accompanied by fits of crying with no seeming cause.

3. Low amounts of L-tryptophan. This is an essential amino acid and is the precursor to one of the most important neurotransmitters, serotonin. Tryptophan helps to raise the levels of serotonin in the brain. Serotonin is needed to regulate sleep, secrete pituitary hormones, and perceive pain. Serotonin is most often abnormally low in depressed people. Tryptophan is found abundantly in milk and turkey. After a carbohydrate rich meal, insulin causes competing amino acids such as tyrosine, phenylalanine, and leucine, to leave the blood and enter muscle tissue. With fewer amino acids vying for entry, more tryptophan enters the brain and is converted into serotonin. Increased serotonin levels results in increased relaxation and drowsiness. You can try this out on yourself. Try eating a meal high in carbohydrates, pasta with a fruit dessert and see how you feel compared with a high protein lunch, fish with vegetable.

4. Candidiasis, a chronic yeast infection of candida albicans, also has associated mental symptoms including feelings of disorientation, confusion and being out of control. On the physical level one may experience joint and muscle ache and pain, as well as bodily pain that is not associated with any apparent cause.

These are a just a few possible reasons one suffers from depression. Depression is an illness, which involves the entire body. In naturopathic as well as Chinese medicine, herbs and herbal combinations may be used to bring balance back into the body, as well as counter fatigue and debility often associated with depression. Persons on antidepressant drugs should not stop or alter any currently prescribed medication without consulting with the physician before trying herbal remedies.

Herbs are very much like the foods we eat, and in fact some of what we eat such as parsley, ginger, garlic, onion, thyme, rosemary are actually herbs and can be used therapeutically. Like food, herbs contain different therapeutic substances such as: vitamins, minerals, trace minerals, and active ingredients such as: volatile oils, alkaloids, flavonoids, bitters, mucilage, saponins, anthraquinones and tannins. Herbs may be used in many forms, such as teas, tinctures, capsules, tablets, caplets, lozenges, syrups, compresses, poultices, sprays, liniments, and oils.

It is important to remember that herbal preparations, whether they are intended for the common cold or depression, cannot stand alone in their effectiveness as a treatment. Herbs are a piece of the puzzle which includes a balanced diet suitable to one's lifestyle and body type, exercise, and designated periods of rest in whatever form that may take. But at least it is a start. If you suffer from depression, talk to a naturopathic physician and know that there are natural remedies out there for you to try.

About the Author: R. Fredriksen is the Vice President of Nutrition Dome, a leading provider of pioneer nutritional formulas. For more information, please visit www.nutritiondome.com.